Our Gemara on Amud Aleph states a principle that the blood of offerings does not nullify each other even when mixed. If the blood of a firstborn offering was mixed with blood of other sacrificial animals, the blood shall be sacrificed together, as the blood of firstborn offerings is not nullified.

Similar to the Sefas Emes (Acharei Mos) that we discussed on dappim 75 and 76, even mitzvos and rituals of lesser holiness occupy their own distinct space. Tiferes Shlomo (Moadim Purim 15 and Rosh Chodesh) understands this as a general principle and explains it in reference to the Rosh Chodesh liturgy on Shabbos. Despite the fact that Shabbos is holier (as evidenced by the many restrictions on work and the recitation of Kiddush), the majority of the Mussaf liturgy on Shabbos Rosh Chodesh is devoted to Rosh Chodesh, and both sacrifices are offered. The item of lesser holiness is not insignificant and cannot be negated. 

Similarly, the physical world, while most removed from God, occupies an essential place and function. Furthermore, Sod Yesharim asserts: At times, even a generally wicked person might be presented with a mitzvah that, if he fulfills it, will accomplish something that no righteous person could achieve.

The profound truth is that every person, aspect, state, and experience in this world is a unique opportunity to fulfill God’s will and be part of the plan. Even when the appearance or objective assessment is inferior, we don’t really know what it means or how important it is.